[New Publication] High-Purity Production of Endothelial Cells from Human Pluripotent Stem Cells

Authors: Koki Yoshimoto, Ririka Okaichi, Kei Iida, Shiho Terada, and Ken-ichiro Kamei Our latest paper, “High-Purity Production of Endothelial Cells from Human Pluripotent Stem Cells”, has been published in Cell Therapy & Engineering Connect. We report a simple, sorting-free method to produce over 90% pure endothelial cells from human pluripotent Read more…

[New Publication] Self-Boosting Nanoparticles to Enhance Cancer Therapy

Thrilled to share our latest work in collaboration with Shenyang Pharmaceutical University, now published in the International Journal of Pharmaceutics: Title:Self-amplifying ROS-responsive trinity nanodelivery system for enhanced cancer therapy Highlights: 🧪 This study showcases the power of integrating nanotechnology with advanced in vitro and in vivo models to address ferroptosis Read more…

[New Publication (Review)] Peptide-based fluorescent Probes for cancer diagnosis and surgery, published in Biosensors & Bioelectronics!

I’m thrilled to share our latest review article, published in Biosensors & Bioelectronics, on the advancements of peptide-based fluorescent probes for tumor imaging. This work is the result of a wonderful collaboration with Prof. Hao Wang at the CAS Center for Excellence in Nanoscience, China. Fluorescent contrast agents are essential Read more…

[New publication] Nanodiamonds as a temperature sensor, published in Sensors & Actuators A: Physical

We are excited to share our latest research published in Sensors & Actuators A: Physical! Title: Microfluidics-guided fluorescent nanodiamond assembly method for highly sensitive thermometry Authors: Keita Saikawa, Masaya Zetsu, Daiki Ueshima, Taiichi Shikama, Ken-ichiro Kamei, Osamu Tabata, Yoshikazu Hirai In this study, we tackled a key challenge in fluorescent nanodiamond (FND)-based thermometry—enhancing sensitivity for practical applications. FNDs with nitrogen vacancy centers (NVCs) Read more…

[New Publication] Hybrid adipocyte-derived exosome nano platform for potent chemo-phototherapy in targeted hepatocellular carcinoma

Our collaborative research paper with Shenyang Pharmaceutical University is now published in the Journal of Controlled Release. Xinying Liu, Jiaxin Zhang, Shunzhe Zheng, Meng Li, Wenqian Xu, Jianbin Shi, Ken-Ichiro Kamei, Chutong Tian [Abstract] The high prevalence and severity of hepatocellular carcinoma (HCC) present a significant menace to human health. Read more…

私達の研究成果が「Frontiers in Bioeng. Biotechnol.」誌に掲載されました!

私達の研究成果が「Frontiers in Bioeng. Biotechnol.」誌に掲載されました! 本研究は、大学院生の吉本くん、短期留学生のNicolas, Kaylene, Janmesh、共同研究者の平井先生とJiandong、当グループの今村さんと寺田さんによって、達成されました。おめでとうございます! タイトル:Recapitulation of Human Embryonic Heartbeat to Promote Differentiation of Hepatic Endoderm to Hepatoblasts 雑誌:Frontiers in Bioeng. Biotechnol. 著者:K. Yoshimoto, N. Miner, J. Yang, S. Imamura, K. Stocking, H. Patel, S. Terada, Y. Hirai and K. Kamei DOI: 10.3389/fbioe.2020.568092

京大WRC村山教授、遠藤博士課程学生との共同研究成果がGBEに掲載されました!

京大WRC村山教授、遠藤博士課程学生との共同研究成果がGBEに掲載されました!本研究は、比較ゲノミクスを駆使して、iPS細胞作成や維持に重要な遺伝子の進化過程を解析した成果です。オープンアクセスですので、どなたでも読むことができます。 (Feature Imageは©高宮ミンディ/京都大学アイセムス – CC BY 4.0) 書誌情報 論文タイトル:“Genetic signatures of evolution of the pluripotency gene regulating network across mammals”(参考訳:哺乳類における多能性制御遺伝子ネットワークの進化の遺伝的な痕跡) 著者:Yoshinori Endo, Ken-ichiro Kamei*, Miho Inoue-Murayama* (*は本研究全般に関する責任著者) Geneme Biology and Evolution|DOI: 10.1093/gbe/evaa169

私たちのビデオプロトコールがJoVEにて公開されました!

私たちのビデオプロトコール がJoVEにて公開されました。 この実験は、私たちが2017年にSmallにて発表した論文 に基づいています。 このビデオを参考に、ぜひ私たちの実験をやってみてください! ABSTRACT Cellular microenvironments consist of a variety of cues, such as growth factors, extracellular matrices, and intercellular interactions. These cues are well orchestrated and are crucial in regulating cell functions in a living system. Although a number of researchers have attempted to investigate the correlation between environmental Read more…

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