55. Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration, X.L. Liu, E. Zu, X. Chang, X.W. Ma, Z.Q. Wang, X.T. Song, X.G. Li, Q. Yu, K. Kamei, T. Hayashi, K. Mizuno, S. Hattori, H. Fujisaki, T. Ikejima, D. O. Wang, Dis. Model Mech., (in press); DOI: 10.1242/dmm.049290

54. Triglyceride-Mimetic Structure-Gated Prodrug Nanoparticles for Smart Cancer Therapy, C. Tian, J. Guo, Y. Miao, S. Zheng, B. Sun, M. Sun, Q. Ye, W. Liu, S. Zhou, K. Kamei*, Z. He*, J. Sun*, J. Med. Chem. 64(21), 15936–15948(2021); DOI: 10.1021/acs.jmedchem.1c01328

53. A Design Method of Organ-on-a-Chip with Highly Accurate Measurement of Trans-Epithelial Electrical Resistance, T. Miyazaki, Y. Hirai, K. Kamei, T. Tsuchiya, O. Tabata, IEEJ Transactions on Sensors and Micromachines, 141(7), 237-244, (2021)

52. Spatiotemporal determination of metabolite activities in the corneal epithelium on a chip, R. Abdalkader, R. Chaleckis, C.E. Wheelock, K. Kamei*, Experimental Eye Research, 209, 108646, (2021); DOI: 10.1016/j.exer.2021.108646

51. Evaluation of the effects of solvents used in the fabrication of microfluidic devices on cell cultures, X. Wen, S. Takahashi, K. Hatakeyama, K. Kamei*, Micromachines, 12(5), 550 (2021); DOI: 10.3390/mi12050550

50. Cyclo olefin polymer-based solvent-free mass-productive microphysiological systems, M. Yamanaka, X. Wen, S. Imamura, R. Sakai, S. Terada, K. Kamei*, Biomed. Mater. 16(3), 035009 (2021); DOI:10.1088/1748-605X/abe660

49. Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes, R. Abdalkader, R. Chaleckis, I. Meister, R. Zhang, C.E. Wheelock, K. Kamei, Anal. Sci., 37(7), 1049-1052, (2021); DOI: 10.2116/analsci.20N032


48. Terahertz pulse-altered gene networks in human induced pluripotent stem cells, T. Tachizaki, R. Sakaguchi, S. Terada, K. Kamei, and H. Hirori, Optics Letters, 45(21), 6078-6081 (2020); DOI: 10.1364/OL.402815

47. Design Strategy of Electrode Patterns Based on Finite Element Analysis in Microfluidic Device for Trans-Epithelial Electrical Resistance (TEER) Measurement, T. Miyazaki, Y. Hirai, K. Kamei, T. Tsuchiya, O. Tabata, IEEJ Trans. SM140-E (2020), accepted (in Japanese)

46. Recapitulation of Human Embryonic Heartbeat to Promote Differentiation of Hepatic Endoderm to Hepatoblasts, K. Yoshimoto, N. Miner, J. Yang, S. Imamura, K. Stocking, H. Patel, S. Terada, Y. Hirai and K. Kamei, Frontiers in Bioeng. Biotechnol. 8, 568092 (2020); DOI: 10.3389/fbioe.2020.568092

45. Genetic signatures of evolution of the pluripotency gene regulating network across mammals, Y. Endo, K. Kamei, M. Inoue-Murayama, Genome Biol. Evol. (in press); DOI: 10.1093/gbe/evaa169

44. Multi-corneal barriers-on-a-chip to recapitulate eye blinking shear stress forces, R. Abdalkader, K. Kamei, Lab Chip, 15(2), 4277-4285 (2020); DOI: 10.1039/C9LC01256G

43. Randomness and optimality in enhanced DNA ligation with crowding effects, TY Shiraki, K. Kamei, YT Maeda, Physical Review Research, 2, 013360 (2020)


42. Three-dimensional cultured liver-on-a-Chip with mature hepatocyte-like cells derived from human pluripotent stem cells, K. Kamei, M. Yoshioka, S. Terada, Y. Tokunaga, Y. Chen. Biomed. Microdev. 21(3), 73 (2019); DOI: 10.1007/s10544-019-0423-8

41. 生体機能の再現を目指したbody-on-a-chip, K. Yoshimoto, K. Kamei, Farumashia, 55(5), 427-431 (2019); DOI: 10.14894/faruawpsj.55.5_427 (Japanese)

40. Novel Microfluidic Device Integrated with a Fluidic-Capacitor to Mimic Heart Beating for Generation of Functional Liver Organoids, J. Wu, Y. Hirai, K. Kamei, T. Tsuchiya, O. Tabata, IEEJ Transactions on Sensors and Micromachines, 139(7), 209‐216 (2019); DOI: 10.1541/ieejsmas.139.209


39. Genetic signatures of lipid metabolism evolution in Cetacea since the divergence from terrestrial ancestor, Y. Endo, K. Kamei*, M. Inoue-Murayama, J. Evolutionary Biology, (2018); DOI: 10.1111/jeb.13361

38. Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array, Y. Mashimo, M. Yoshioka, Y. Tokunaga, C. Fockenberg, S. Terada, Y. Koyama, T. Shibata-Seki, K. Yoshimoto, R. Sakai, H. Hakariya, L. Liu, T. Akaike, E. Kobatake, S.E. How, M. Uesugi, Y. Chen, K. Kamei*Journal of Visualized Experiments (JoVE), 139, e57377 (2018); DOI:10.3791/57377


37. Integrated Heart/Cancer on a chip to reproduce the side effects of anti-cancer drug in vitro, K. Kamei,* Y. Kato, Y. Hirai,*, S. Ito, J. Satoh, A. Oka, T. Tsuchiya, Y. Chen and O. Tabata, RSC Advances, 7, 36777-36786 (2017); DOI: 10.1039/C7RA07716E (*Corresponding authors)


36. Microfluidic-nanofiber hybrid array for screening of cellular microenvironments, K. Kamei‡*, Y. Mashimo‡, M. Yoshioka, Y. Tokunaga, C. Fockenberg, S. Terada, M. Nakajima, T. Shibata-Seki, L. Liu, T. Akaike, E. Kobatake, E. S. How, M. Uesugi and Y. Chen*, Small, 13(18), 1603104 (2017); DOI: 10.1002/smll.201603104 (*Corresponding authors; ‡These authors contributed equally to this work.)


35. Nano-on-micro fibrous extracellular matrices for scalable expansion of human ES/iPS cells,  Liu†, K. Kamei†*, M. Yoshioka, M. Nakajima, J.J. Li, N. Fujimoto, S. Terada, Y. Tokunaga, Y. Koyama, H. Sato, K. Hasegawa, N. Nakatsuji and Y. Chen, Biomaterials, 124, 47-54 (2017); DOI: 10.1016/j.biomaterials.2017.01.039 (*Corresponding authors)

Vac-High PC-Std. 10kV x500 (47mm)


34. Characterization of phenotypic and transcriptional differences in human pluripotent stem cells under two- and three-dimensional culture conditions, K. Kamei*, Y. Koyama, Y. Tokunaga, Y. Mashimo, M. Yoshioka, C. Fockenberg, R. Mosbergen, O. Korn, C. Wells and Y. Chen*, Advanced Healthcare Materials, (2016); DOI: 10.1002/adhm.201600893


33. ヒト組織をin vitroで再現するBody on a Chip: マイクロ流体デバイス技術でES/iPS細胞由来臓器細胞の3次元培養と創薬応用, T. Okamoto, K. Kamei, 創薬のひろば, 3 (2016), in press (in Japanese, essay)

32. Development of a Body-on-a-Chip Using 3-D Microstructuring Technique (3 次元微細加工を応用した Body on a Chip の開発), Y. Kato, Y. Hirai, K. Kamei, T. Tsuchiya and O. Tabata, IEEJ Trans. SM, 136(6), 229-236 (2016) (in Japanese).


31. Directing and boosting of cell migration by the entropic force gradient in polymer solution, T. Fukuyama, A. Fuke, M. Mochizuki, K. Kamei and Y. T. Maeda, Langmuir 31(46),  12567–12572 (2015); DOI: 10.1021/acs.langmuir.5b02559

30. Oscillation and collective conveyance of water-in-oil droplets by microfluidic bolus flow, Ohnuma, M. Ichikawa, K. Kamei, Y. T. Maeda, Applied Physics Letters 107, 074102 (2015); DOI: 10.1063/1.4928753

29. 3D printing of soft lithography mold for rapid production of polydimethylsiloxane-based microfluidic devices for cell stimulation with concentration gradients, K. Kamei*, Y. Mashimo, Y. Koyama, C. Fockenberg, M. Nakashima, M. Nakajima, J.J. Li and Y. Chen*, Biomed. Microdev. 17(2), (2015); DOI: 10.1007/s10544-015-9928-y (*Corresponding authors)


28. Nanofibrous gelatin substrates for culture and long-term expansion of human pluripotent stem cells, L. Liu, M. Yoshioka, M. Nakajima, A. Ogasawara, J. Liu, K. Hasegawa, S. Li, J. Zou, N. Nakatsuji, K. Kamei* and Y. Chen,* Biomaterials 35(24), 6259-6267 (2014); DOI: 10.1016/j.biomaterials.2014.04.024 (*Corresponding authors)

27. Fibrous Architectures of Porous Coordination Polymers/Alumina Composites Fabricated by Coordination Replication, M. Nakahama, J. Reboul, K. Kamei, S. Kitagawa and S. Furukawa, Chemistry Letters 43(7), 1052-1054 (2014); DOI: 10.1246/cl.140291


26. Localized cell stimulation by nitric oxide using a photoactive porous coordination polymer platform, S. Diring,  D. O. Wang,  C. Kim,  M. Kondo,  Y. Chen,  S. Kitagawa, K. Kamei* and S. Furukawa*, Nature Communications 4, Article number: 2684 (2013); DOI:10.1038/ncomms3684 (*Corresponding authors)

25. Body on a Chip: Re-creation of a living system in vitro., K. Kamei, Y. Hirai and O. Tabata, IEEE Nanotechnology Magazine 7(3), 6-14 (2013); DOI: 10.1109/MNANO.2013.2275024

24. Cutting-edge microfabricated biomedical tools for human pluripotent stem cell research, K. Kamei, Journal of Laboratory Automation (JALA) (2013); DOI: 10.1177/2211068213495394

23. Integration of Porous Coordination Polymers and Gold Nanorods into Core-shell Mesoscopic Composites towards Light-induced Molecular Release, K. Khaletskaya, J. Reboul, M. Meilikhov, M. Nakahama, S. Diring, M. Tsujimoto, S. Isoda, F. Kim, K. Kamei, R. A. Fischer, S. Kitagawa, and S. Furukawa, J. Am. Chem. Soc.135(30), 10998-11005 (2013); DOI: 10.1021/ja403108x

22. Phenotypic and transcriptional modulation of human pluripotent stem cells induced by nano/microfabrication materials, K. Kamei,‡* Y. Hirai,‡ Y. Makino, M. Yoshioka, Q. Yuan, M. Nakajima, Y. Chen, and O. Tabata,* Advanced Healthcare Materials2(2), 287-291 (2013); DOI: 10.1002/adhm.201200283 (*Corresponding authors; ‡These authors contributed equally to this work.)


21. Chemically defined scaffolds created with electrospun synthetic nanofibers to maintain mouse embryonic stem cell culture under feeder-free conditions, L. Liu, Q. Yuan, J. Shi, X. Li, D. June, K. Yamauchi, N. Nakatsuji, K. Kamei* and Y. Chen* , Biotechnol. Lett., 34(10), 1951-1957 (2012); DOI: 10.1007/s10529-012-0973-9 (*Corresponding authors)


20. Integrated and diffusion-based micro-injectors for open access cell assays, X. Li, L. Liu, L. Wang, K. Kamei, Q. Yuan, F. Zhang, J. Shi, A. Kusumi, M. Xie, Z. Zhao and Y. Chen, Lab Chip, 11(15), 2612-2617 (2011)

19. Delivery of Intact Transcription Factor by Using Self-Assembled Supramolecular Nanoparticles, Y. Liu, H. Wang, K. Kamei, M. Yan, K.-J. Chen, L. Shi, Y. Lu and H.-R. Tseng, Angew. Chem. Int. Ed. Engl. 50(13), 3058-3062 (2011)


18. Microfluidic Image Cytometry for Quantitative Single-Cell Profiling of Human Pluripotent Stem Cells in Chemically Defined Conditions, K. Kamei,† M. Ohashi, E. Gschweng, Q. Ho, J. Suh, Z. T. F. Yu, J. Tang, A. T. Clark, A. D. Pyle, M. A. Teitell, K.-B. Lee, O. N. Witte and H.-R. Tseng,†, Lab. Chip, 10(9), 1113-1119 (2010) (†Corresponding authors)

17. A rapid pathway toward a superb gene delivery system: Programming structural and functional diversity into a supramolecular nanoparticle library, H. Wang, K. Liu, K.-J. Chen, Y. Lu, S. Wang, W.-Y. Lin,F. Guo, K. Kamei, Y.-C. Chen, M. Ohashi, M. Wang, X.-Z. Zhao, C. K.-F. Shen, and H.-R. Tseng, ACS Nano4(10), 6235-6243 (2010)

16. A differential capture assay for antibody selection against cell surface targets, D. J. Sherman, V. E. Kenanova, E. J. Lepin, k. E. McCabe, K. Kamei, M. Ohashi, s. Wang, H.-R. Tseng, A. M. Wu and C. P. Behrenbruch, Anal. Biochem.401(2), 173-181 (2010)

15. Compensatory Hypertrophy Induced by Ventricular Cardiomyocyte Specific COX-2 Expression in Mice, J. M. Streicher, K. Kamei, T. Ishikawa, H. R. Herschman and Y. Wang, J. Mol. Cell. Cardiol. 49(1), 88-94 (2010)

14. A Small Library of DNA-Encapsulated Supramolecular Nanoparticles for Targeted Gene Delivery, H. Wang, K.-J. Chen, S. Wang, M. Ohashi, K. Kamei, J. Sun, J.H. Ha, K. Liu and H.-R. Tseng, Chem. Commun. 46(11), 1851-1853 (2010)

13. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens, J. Sun, M. D. Masterman-Smith, N. A. Graham, J. Jiao, J. Mottahedeh, D. R. Laks, M. Ohashi, J. DeJesus, K. Kamei, K.-B. Lee, H. Wang, Z. T. F. Yu, Y.-T. Lu, S. Hou, K. Li, M. Liu, N. Zhang, S. Wang, B. Angenieux, E. Panosyan, E. R. Samuels, J. Park, D. Williams, V. Konkankit, D. Nathanson, R. M. van Dam, M. E. Phelps, H. Wu, L. M. Liau, P. S. Mischel, J. A. Lazareff, H. I. Kornblum, W. H. Yong, T. G. Graeber and H.-R. Tseng, Cancer Res. 70(15), 6128-6138 (2010)

12. Selectively inhibiting proliferation of human brain cancer cells via multifunctional quantum dot-based siRNA delivery, J. Jung, A. Solanki, K. A. Memoli, K. Kamei, H. Kim, L. J. Williams, H.-R. Tseng, and K.-B. Lee, Angew. Chem. Int. Ed. Engl. 49(1), 103-107 (2010)


11. Three-Dimensional Nanostructured Substrates Toward Efficient Capture of Circulating Tumor Cells, S. Wang, H. Wang, J. Jiao, K. Kamei, K.-J. Chen, J. Sun, D. Sherman, G. E. Owens, H. Wu, C. Behrenbruch and H.-R. Tseng, Angew. Chem. Int. Ed. Engl. 48(47), 8970-8973 (2009)

10. A supramolecular approach for preparation of size-controllable nanoparticle, H. Wang, S. Wang, H. Su, K.-J. Chen, A. L. Armijo, W.-Y. Lin, Y. Wang, J. Sun, K. Kamei, J. Czernin, C. G. Radu and H.-R. Tseng, Angew. Chem. Int. Ed. Engl48(24), 4344-4348 (2009)

9. An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells, K. Kamei*,S. Guo*, Z. T. F. Yu*, H. Takahashi, E. Gschweng, X. Wang, C. Suh, J. Tang, J. McLaughlin, O. N. Witte, K.-B. Lee and H.-R. Tseng, Lab. Chip9(4), 555-563 (2009) (*These authors contributed equally to this work.)

8. An integrated microfluidic chip for parallel culture and multiparametric analysis of murine and human cells, Z. T. F. Yu*, K. Kamei*, H. Takahashi, C. J. Shu, G. W. He, R. W. Silverman, C. G. Radu, O. N. Witte, K.-B. Lee and H.-R. Tseng, Biomed. Microdev.11, 547-555 (2009) (*These authors contributed equally to this work.)


7. A Microfluidic platform for sequential ligand labeling and cell binding analysis, G. Sui, C.-C. Lee, K. Kamei, H.-J. Li, J. Wang, H. R. Herschman and H.-R. Tseng, Biomed. Microdev.9, 301-305 (2007)


6. Transgenic mouse for conditional, tissue-specific Cox-2 over-expression, K. Kamei, T. Ishikawa and H. R. Herschman, Genesis44, 177-182 (2006)


5. Construction of cell based assessing system for chemicals on immune regulation using electrochemical NO sensor, K. Kamei, M. Mie, Y. Yanagida, M. Aizawa and E. Kobatake, Sens. Actuat. B: Chemical96, 106-112 (2004)

4. Construction of endothelial cellular biosensing system for blood pressure control drugs with electrochemical monitoring of nitric oxide, K. Kamei, T. Haruyama, M. Mie, Y. Yanagida, M. Aizawa and E. Kobatake, Biosens. Bioelectron.19, 1121-1124 (2004)


3. Development of immune cellular biosensing system for assessing chemicals on iNOS signaling activator, K. Kamei, T. Haruyama, M. Mie, Y. Yanagida, M. Aizawa and E. Kobatake, Anal. Biochem.320, 75-81 (2003)

2. Cellular biosensing system for assessing immunomodulating effects on the inducible nitric oxide synthase (iNOS) cascade, K. Kamei, T. Haruyama, M. Mie, Y. Yanagida, E. Kobatake and M. Aizawa, Biotechnol. Lett.25, 321-325 (2003)


1. Cellular biosensing systems in response to drug stimuli, K. Kamei, Intelligent Materials11(3), 21-24 (2002)