I’m thrilled to share our latest review article, published in Biosensors & Bioelectronics, on the advancements of peptide-based fluorescent probes for tumor imaging. This work is the result of a wonderful collaboration with Prof. Hao Wang at the CAS Center for Excellence in Nanoscience, China.
Fluorescent contrast agents are essential for enhancing the sensitivity and accuracy of live optical imaging. However, traditional contrast agents often suffer from significant limitations, such as short half-life, poor biocompatibility, and inadequate tumor targeting, which hinder their effectiveness in imaging-guided applications. Peptides, with their modular design and high specificity, provide a powerful alternative by allowing precise engineering to improve their biological activity and pharmacokinetic properties.
In this review, we explore three key strategies for designing peptide-based fluorescent probes, discussing their distinct mechanisms, innovative aspects, and how they surpass conventional agents in performance. We also highlight their potential applications in tumor diagnosis and image-guided surgery, offering insights into their future clinical translation.
This work contributes to the ongoing efforts to develop more precise, biocompatible, and efficient imaging tools for biomedical applications. I hope this review serves as a valuable resource for researchers and clinicians working at the intersection of nanotechnology, biosensing, and medical imaging.
Read the full paper here: https://www.sciencedirect.com/science/article/pii/S0956566325001290?via%3Dihub
A huge thank you to our collaborators and everyone who supported this work. I look forward to engaging discussions and potential collaborations in this exciting and rapidly evolving field!
#FluorescenceImaging #PeptideProbes #Biosensors #TumorDiagnosis #Bioelectronics #OpticalImaging #MedicalInnovation #Nanoscience
0 Comments