[New Publication] Brain Organoid-on-a-Chip in RSC Advances!

We are thrilled to announce our latest publication in RSC Advances:
“Proof of Concept for Brain Organoid-on-a-Chip to Create Multiple Domains in Forebrain Organoids,” now available!
In collaboration with Prof. Momoko Watanabe at the University of California Irvine, alongside researchers from NYU Abu Dhabi and Kyoto University, our work presents a brain organoid-on-a-chip platform that generates signaling gradients, enabling the induction of topographic forebrain organoids. This approach enhances the regionalization of brain organoids, bringing us closer to faithfully mimicking human brain development and disease states in vitro.
By advancing 3D brain tissue modeling, we aim to deepen our understanding of neurodevelopment and enhance disease modeling capabilities. This proof-of-concept study paves the way for future breakthroughs in brain-on-chip technologies!
Authors: Yuan-Chen Tsai,‡ Hajime Ozaki,‡ Ango Morikawa, Kaori Shiraiwa, Andy Prosvey Pin, Aya Galal Salem, Kenneth Akady Phommahasay, Bret Kiyoshi Sugita, Christine Hein Vu, Saba Mamoun Hammad, Ken-ichiro Kamei,* and Momoko Watanabe*
We look forward to engaging with the scientific community to further explore applications of brain organoid-on-a-chip systems! Let’s push the boundaries of stem cell biology, neuroscience and bioengineering together.